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Beta-blockers (atenolol, bisoprolol, metoprolol, nadolol, pindolol, propranolol, and timolol) reduce the work load on the heart as well as having other effects. It has approximately one fortieth of the beta-adrenergic blocking activity of propranolol {01}, which may become clinically significant in some patients {61} {62}. Propranolol should only be given during pregnancy when benefit outweighs risk. propranolol to healthy volunteers under steady-state conditions had no relevant effect on either drug’s bioavailability. Propranolol controls, but does not cure, high blood pressure (hypertension). There are a number of abnormalities associated with the use of propranolol during pregnancy, but many of these may be attributable to underlying diseases.
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